Periodontitis, or gum disease, causes excessive gum bleeding and bone loss, which eventually leads to tooth loss. In fact, periodontitis is the leading cause of adult tooth loss in the US. The swelling and bleeding associated with gum disease is caused by an over-active immune response to the bacteria in your mouth. As we grow older, we become more susceptible to inflammatory diseases, including gum disease. Your Corona dentists explore new research from Queen Mary, University of London that may explain why gum disease is more common with old age.
The Immune System Controller
When your body detects infection, your immune system immediately reacts to combat the infection. White blood cells are your immune system’s agents in this battle and a common sign that your body is fighting infection is inflammation. When harmful bacteria colonies increase in number in your mouth, your body responds by sending white blood cells in response to the threat, and your gums often become inflamed while your immune system goes to work. The University of London study revealed that gum health deterioration is associated with a drop in the levels of a chemical called Del-1. The purpose of this protein is to restrain the immune system by preventing white blood cells from attacking the mouth (thus reducing inflammation). (more…)











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